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How Does PRP Work?

The human body has a remarkable capacity to heal itself. Regeneration of new tissue is accomplished by stem cells and is fostered by growth factors and hormones. Platelet-rich plasma (PRP) is an emerging treatment in many medical specialties: orthopedics, wound healing, surgery, aesthetic and sexual medicine.

How does Platelet Rich Plasma (PRP) work?

The Science of PRP: The body signals platelets and other components in our blood supply to migrate to the site of injury. Platelets are the injury’s first responders, and under normal conditions these platelets release various factors that initiate and subsequently stimulate repair, and promote new blood vessel development to accelerate tissue regeneration.

A concentrated PRP that is activated leads to the release of many bioactive proteins responsible for regeneration by growth factors and by attracting mesenchymal stem cells to the treatment area Inside the platelet are 2 types of granules, namely, alpha granules and dense bodies. Alpha granules contain the clotting and growth factors that are released in the healing process.

Normally at the resting state, platelets require a trigger to activate and become a participant in wound healing and hemostasis. Growth factors and other cytokines in platelets include the following: platelet-derived growth factor, transforming growth factor, fibroblast growth factor, insulin like growth factor 1, insulin like growth factor 2, vascular endothelial growth factor, epidermal growth factor, interleukin 8, keratinocyte growth factor, and connective tissue growth factor.

Are Platelet Rich Plasma (PRP) procedures FDA approved?

Platelet Rich Plasma (PRP) procedures are not approved or disapproved by FDA because PRP is not a drug. The FDA has approved the PRP harvesting kits that are used in the platelet collection process and they have been deemed safe. PRP has always shown to be safe and is effective at regeneration, healing and rejuvenation in many different medical specialties.

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